Title : Challenge and perspective: the relevance of ultraviolet (UV) radiation and the vitamin D endocrine system (VDES) for psoriasis and other inflammatory skin diseases.

Pub. Date : 2017 Mar 16

PMID : 28054069






1 Functional Relationships(s)
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1 Human keratinocytes contain the enzymatic machinery (CYP27B1) for the synthesis of the biologically most active natural vitamin D metabolite 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), representing an autonomous vitamin D3 pathway. Cholecalciferol cytochrome P450 family 27 subfamily B member 1 Homo sapiens