Title : β2-adrenergic receptor control of endosomal PTH receptor signaling via Gβγ.

Pub. Date : 2017 Mar

PMID : 28024151






3 Functional Relationships(s)
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1 Here we found that the beta2-adrenergic receptor, which induces a short cAMP response, prolongs nuclear cAMP and protein kinase A (PKA) activation by promoting endosomal cAMP production in parathyroid hormone (PTH) receptor signaling through the stimulatory action of G protein Gbetagamma subunits on adenylate cyclase type 2. Cyclic AMP adrenoceptor beta 2 Homo sapiens
2 Here we found that the beta2-adrenergic receptor, which induces a short cAMP response, prolongs nuclear cAMP and protein kinase A (PKA) activation by promoting endosomal cAMP production in parathyroid hormone (PTH) receptor signaling through the stimulatory action of G protein Gbetagamma subunits on adenylate cyclase type 2. Cyclic AMP adrenoceptor beta 2 Homo sapiens
3 Here we found that the beta2-adrenergic receptor, which induces a short cAMP response, prolongs nuclear cAMP and protein kinase A (PKA) activation by promoting endosomal cAMP production in parathyroid hormone (PTH) receptor signaling through the stimulatory action of G protein Gbetagamma subunits on adenylate cyclase type 2. Cyclic AMP adrenoceptor beta 2 Homo sapiens