Title : Dmp1 Null Mice Develop a Unique Osteoarthritis-like Phenotype.

Pub. Date : 2016

PMID : 27766035






3 Functional Relationships(s)
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Compound Name
Protein Name
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1 A 8-week treatment of a high phosphate diet significantly rescued the OA-like defect in Dmp1 null mice, supporting the critical role of phosphate homeostasis in maintaining the healthy joint morphology and function. Phosphates dentin matrix protein 1 Mus musculus
2 A 8-week treatment of a high phosphate diet significantly rescued the OA-like defect in Dmp1 null mice, supporting the critical role of phosphate homeostasis in maintaining the healthy joint morphology and function. Phosphates dentin matrix protein 1 Mus musculus
3 Instead, the regulation of phosphate homeostasis by DMP1 via the axis of "FGF23-renal phosphorus reabsorption" is vital for maintaining a healthy joint. Phosphates dentin matrix protein 1 Mus musculus