Title : Icariin promotes osteogenic differentiation of rat bone marrow stromal cells by activating the ERα-Wnt/β-catenin signaling pathway.

Pub. Date : 2016 Dec

PMID : 27764755






1 Functional Relationships(s)
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1 Additionally, icariin (0.1muM) significantly up-regulated the expression of osteogenic genes (Runx2, osteopotin, DLX5, osteocalcin, collagen type I, and ERalpha) and Wnt signal members (beta-catenin, Lef1, TCF7, c-jun, c-myc, and cyclin D). icariin bone gamma-carboxyglutamate protein Rattus norvegicus