Title : Anticancer effect of thalidomide in vitro on human osteosarcoma cells.

Pub. Date : 2016 Dec

PMID : 27748909






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Thalidomide was added to osteosarcoma cells and studied by cytotoxicity assay, evaluating apoptosis, cell cycle arrest, mitochondrial membrane potential (DeltaPsim), and reactive oxygen species (ROS) levels and the expression of Bcl-2, Bax, caspase-3 and NF-kappaB. Thalidomide BCL2 apoptosis regulator Homo sapiens
2 By western blot analysis, thalidomide resulted in the decreasing expression of Bcl-2 and NF-kappaB, and the increasing expression of Bcl-2/Bax and caspase-3. Thalidomide BCL2 apoptosis regulator Homo sapiens
3 By western blot analysis, thalidomide resulted in the decreasing expression of Bcl-2 and NF-kappaB, and the increasing expression of Bcl-2/Bax and caspase-3. Thalidomide BCL2 apoptosis regulator Homo sapiens