Title : Slowly Delivered Icariin/Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells to Promote the Healing of Calvarial Critical-Size Bone Defects.

Pub. Date : 2016

PMID : 27721833






1 Functional Relationships(s)
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1 In in vitro cellular experiments, icariin at optimal concentration (10-6 mol/L) could significantly upregulate the osteogenesis- and angiogenesis-related genes and proteins, such as Runx2, ALP, osteocalcin, vascular endothelial growth factors, and fibroblast growth factors, as well as the mineralization of BMSCs. icariin bone gamma-carboxyglutamate protein Rattus norvegicus