Title : Disruption of a miR-29 binding site leading to COL4A1 upregulation causes pontine autosomal dominant microangiopathy with leukoencephalopathy.

Pub. Date : 2016 Nov

PMID : 27666438






2 Functional Relationships(s)
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1 Disruption of a miR-29 binding site leading to COL4A1 upregulation causes pontine autosomal dominant microangiopathy with leukoencephalopathy. mir-29 collagen type IV alpha 1 chain Homo sapiens
2 RT-qPCR analyses of patients" primary fibroblasts and luciferase reporter assays strongly favor an upregulation of COL4A1 mediated by disruption of miR-29 binding to its target site. mir-29 collagen type IV alpha 1 chain Homo sapiens