Title : ATF4 regulates arsenic trioxide-mediated NADPH oxidase, ER-mitochondrial crosstalk and apoptosis.

Pub. Date : 2016 Nov 1

PMID : 27638049






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Following ATO treatment, ATF4 activates NADPH oxidase by promoting assembly of the enzyme components Rac-1/P47phox/P67phox, which generates ROS/superoxides. Superoxides Rac family small GTPase 1 Homo sapiens