Title : NOX2 amplifies acetaldehyde-mediated cardiomyocyte mitochondrial dysfunction in alcoholic cardiomyopathy.

Pub. Date : 2016 Sep 14

PMID : 27624556






1 Functional Relationships(s)
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1 Echocardiography revealed that ALDH-2(-/-)/gp91(phox-/-) mice were protected from ACA-overload-induced HF after 5 weeks of 2% EtOH-diet, demonstrating that NOX2-derived O2( -) contributes to the development of ACM. Superoxides cytochrome b-245, beta polypeptide Mus musculus