Title : Osteoblasts activate the Nrf2 signalling pathway in response to arsenic trioxide treatment.

Pub. Date : 2016 Oct

PMID : 27592447






2 Functional Relationships(s)
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1 Experiments using inhibitors of antioxidant enzymes in the presence of arsenic trioxide-treated osteoblasts demonstrated that glutathione and superoxide dismutase were responsible for reducing oxidative stress, caspase-3 activity, and apoptosis and that heat shock proteins helped reduce caspase-3 activity. Arsenic Trioxide caspase 3 Homo sapiens
2 Experiments using inhibitors of antioxidant enzymes in the presence of arsenic trioxide-treated osteoblasts demonstrated that glutathione and superoxide dismutase were responsible for reducing oxidative stress, caspase-3 activity, and apoptosis and that heat shock proteins helped reduce caspase-3 activity. Arsenic Trioxide caspase 3 Homo sapiens