Title : Molecular and histological changes in cerebral cortex and lung tissues under the effect of tramadol treatment.

Pub. Date : 2016 Aug

PMID : 27470363






1 Functional Relationships(s)
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1 On molecular level, the expression of the pro-apoptotic Bax and Caspase-3 showed a significant increase whereas the anti-apoptotic Bcl-2 decreased markedly indicating that tramadol is harmful at cellular level and can induce apoptotic changes in brain tissues. Tramadol BCL2 associated X, apoptosis regulator Rattus norvegicus