Title : TLR4/IFN╬│ pathways induce tumor regression via NOS II-dependent NO and ROS production in murine breast cancer models.

Pub. Date : 2016 May

PMID : 27467924






1 Functional Relationships(s)
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1 Mechanistic investigations revealed that nitric oxide (NO), superoxide and peroxynitrite produced by uncoupling of inducible NO synthase (NOS II) in cancer cells are key mediators of ALA and IFNgamma-mediated tumor growth inhibition. Superoxides interferon gamma Mus musculus