Title : Nicotine enhances the malignant potential of human pancreatic cancer cells via activation of atypical protein kinase C.

Pub. Date : 2016 Nov

PMID : 27424921

1 Functional Relationships(s)
Compound Name
Protein Name
1 We also found that nicotine induced phosphatidylinositol 3-kinase (PI3K) signal activation, and a specific inhibitor of the nicotine acetylcholine receptor (nAChR) as well as knockdown of nAChR prevented nicotine-mediated Akt phosphorylation and aPKC activation. Nicotine AKT serine/threonine kinase 1 Homo sapiens