Title : Discovery of a novel ROCK2 inhibitor with anti-migration effects via docking and high-content drug screening.

Pub. Date : 2016 Aug 16

PMID : 27354305






1 Functional Relationships(s)
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1 Through the combined virtual and high-content drug screening, the compound 1,3-benzodioxol-5-yl[1-(5-isoquinolinylmethyl)-3-piperidinyl]-methanone (BIPM) was identified as a novel and potent ROCK2 inhibitor. N-[4-(2-Benzimidazolyl)phenyl]maleimide Rho associated coiled-coil containing protein kinase 2 Homo sapiens