Title : North American ginseng inhibits myocardial NOX2-ERK1/2 signaling and tumor necrosis factor-α expression in endotoxemia.

Pub. Date : 2016 Sep

PMID : 27317946






1 Functional Relationships(s)
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1 Myocardial expression of tumor necrosis factor-alpha (TNF-alpha), a major pro-inflammatory cytokine that causes cardiac dysfunction, was upregulated in mice with endotoxemia, which was accompanied by increases in NOX2 expression, superoxide generation and ERK1/2 phosphorylation. Superoxides cytochrome b-245, beta polypeptide Mus musculus