Title : Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor Degradation.

Pub. Date : 2016 Aug 5

PMID : 27284008






1 Functional Relationships(s)
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1 We further showed that the sdAb-Fcs do not affect binding of PCSK9 to the LDLR but rather block its induced cellular LDLR degradation. sdab low density lipoprotein receptor Homo sapiens