Title : Pyrrolidine dithiocarbamate inhibits superoxide anion-induced pain and inflammation in the paw skin and spinal cord by targeting NF-κB and oxidative stress.

Pub. Date : 2016 Jun

PMID : 27160222






1 Functional Relationships(s)
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1 Intraplantar injection of superoxide anion activated NF-kappaB and increased cytokine production (IL-1beta, TNF-alpha and IL-10) and oxidative stress (nitrite and lipid peroxidation levels) at the primary inflammatory foci and in the spinal cord (L4-L6). Superoxides tumor necrosis factor Mus musculus