Title : LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48.

Pub. Date : 2016 Aug

PMID : 27125555






2 Functional Relationships(s)
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1 LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48. Sulbactam OXA-48 Klebsiella pneumoniae
2 METHODS: The OXA-48 gene was cloned and expressed in Klebsiella pneumoniae and Escherichia coli in order to obtain MICs in the presence of inhibitors (clavulanic acid, tazobactam and sulbactam) and LN-1-255. Sulbactam OXA-48 Klebsiella pneumoniae