Title : Targeting the AKT pathway: Repositioning HIV protease inhibitors as radiosensitizers.

Pub. Date : 2016 Feb

PMID : 27121513

1 Functional Relationships(s)
Compound Name
Protein Name
1 This review describes the mechanisms by which PI3-K/AKT pathway causes radioresistance and the role of HIV protease inhibitors especially nelfinavir as a potential candidate drug to target the AKT pathway for overcoming radioresistance and its use in various clinical trials for different malignancies. Nelfinavir AKT serine/threonine kinase 1 Rattus norvegicus