Title : Single nucleotide polymorphisms in glutathione S-transferase P1 and M1 genes and overall survival of patients with ovarian serous cystadenocarcinoma treated with chemotherapy.

Pub. Date : 2016 Apr

PMID : 27073511






1 Functional Relationships(s)
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1 The effects of platinum-based drugs are controlled by genes that are involved in DNA detoxification, including glutathione S-transferase (GST)P1 and GSTM1, which have been associated with increased benefits in the chemotherapeutic treatment of patients with ovarian cancer. Platinum glutathione S-transferase kappa 1 Homo sapiens