Title : Downregulation of VEGF and upregulation of TL1A expression induce HUVEC apoptosis in response to high glucose stimuli.

Pub. Date : 2016 Apr

PMID : 26936681






4 Functional Relationships(s)
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Protein Name
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1 Downregulation of VEGF and upregulation of TL1A expression induce HUVEC apoptosis in response to high glucose stimuli. Glucose TNF superfamily member 15 Homo sapiens
2 The results showed that the downregulation of VEGF in combination with the upregulation of TL1A in response to high glucose levels led to enhanced HUVEC apoptosis. Glucose TNF superfamily member 15 Homo sapiens
3 Further experiments revealed that silencing high glucose-induced TL1A expression using TL1A small interfering (si)RNA or the overexpression of VEGF by transfection with VEGF DNA resulted in a reduced HUVEC apoptosis rate compared with the controls. Glucose TNF superfamily member 15 Homo sapiens
4 Further experiments revealed that silencing high glucose-induced TL1A expression using TL1A small interfering (si)RNA or the overexpression of VEGF by transfection with VEGF DNA resulted in a reduced HUVEC apoptosis rate compared with the controls. Glucose TNF superfamily member 15 Homo sapiens