Pub. Date : 2016 Feb 25
PMID : 26917416
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Niclosamide induced cell apoptosis via upregulation of ATF3 and activation of PERK in Hepatocellular carcinoma cells. | Niclosamide | eukaryotic translation initiation factor 2 alpha kinase 3 | Homo sapiens |
| 2 | Furthermore, our study revealed that RNA-dependent protein kinase-like kinase (PERK) is activated and its expression is up-regulated in HCC cells which are exposed to niclosamide. | Niclosamide | eukaryotic translation initiation factor 2 alpha kinase 3 | Homo sapiens |
| 3 | It"s suggested that the function of niclosamide was abrogated by PERK inhibitor or absent ATF3. | Niclosamide | eukaryotic translation initiation factor 2 alpha kinase 3 | Homo sapiens |