Title : Dietary compound α-asarone alleviates ER stress-mediated apoptosis in 7β-hydroxycholesterol-challenged macrophages.

Pub. Date : 2016 May

PMID : 26893256






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Immunoblotting showed that the oxysterol activated the ER transmembrane resident kinases of IRE1alpha, PERK and ATF4 and triggered caspase-12 signaling cascades, which was reversed by alpha-asarone. Oxysterols caspase 12 Mus musculus