Title : Acute knockdown of the insulin receptor or its substrates Irs1 and 2 in 3T3-L1 adipocytes suppresses adiponectin production.

Pub. Date : 2016 Feb 18

PMID : 26888756






1 Functional Relationships(s)
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1 Efficient knockdown of either Insr or Irs1/2 was achieved by conditional shRNA expression, severely attenuating insulin-stimulated AKT phosphorylation and glucose uptake. Glucose insulin receptor Homo sapiens