Title : Dynamics and plasticity of the epithelial to mesenchymal transition induced by miR-200 family inhibition.

Pub. Date : 2016 Feb 18

PMID : 26887353






2 Functional Relationships(s)
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1 By developing a potent inhibitor of miR-200 family members (TuD-141/200c), the expression of which is strictly regulatable by the Tet (tetracycline)-On system, we found using a human colorectal cell line, HCT116, that several direct gene target mRNAs (Zeb1/Zeb2, ESRP1, FN1and FHOD1) of miR-200 family were elevated with distinct kinetics. Tetracycline zinc finger E-box binding homeobox 2 Homo sapiens
2 By developing a potent inhibitor of miR-200 family members (TuD-141/200c), the expression of which is strictly regulatable by the Tet (tetracycline)-On system, we found using a human colorectal cell line, HCT116, that several direct gene target mRNAs (Zeb1/Zeb2, ESRP1, FN1and FHOD1) of miR-200 family were elevated with distinct kinetics. Tetracycline zinc finger E-box binding homeobox 2 Homo sapiens