Title : Biochemical and behavioral effects of PDE10A inhibitors: Relationship to target site occupancy.

Pub. Date : 2016 Mar

PMID : 26522433






2 Functional Relationships(s)
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1 Phosphodiesterase 10A (PDE10A) inhibitors increase the functionality of striatal medium spiny neurons and produce antipsychotic-like effects in rodents by blocking PDE10A mediated hydrolysis of cAMP and/or cGMP. Cyclic GMP phosphodiesterase 10A Mus musculus
2 Phosphodiesterase 10A (PDE10A) inhibitors increase the functionality of striatal medium spiny neurons and produce antipsychotic-like effects in rodents by blocking PDE10A mediated hydrolysis of cAMP and/or cGMP. Cyclic GMP phosphodiesterase 10A Mus musculus