Title : Structure-activity relationships of amide-phosphonate derivatives as inhibitors of the human soluble epoxide hydrolase.

Pub. Date : 2015 Nov 15

PMID : 26507430






2 Functional Relationships(s)
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1 In addition, the resulting potent amide-phosphonate compounds had reasonable water solubility, suggesting that substituted phosphonates in amide inhibitors are effective for both inhibition potency on the human sEH and water solubility as a secondary pharmacophore. Organophosphonates epoxide hydrolase 2 Homo sapiens
2 In addition, the resulting potent amide-phosphonate compounds had reasonable water solubility, suggesting that substituted phosphonates in amide inhibitors are effective for both inhibition potency on the human sEH and water solubility as a secondary pharmacophore. Organophosphonates epoxide hydrolase 2 Homo sapiens