Title : Agonist and antagonist effects of tobacco-related nitrosamines on human α4β2 nicotinic acetylcholine receptors.

Pub. Date : 2015

PMID : 26441658






2 Functional Relationships(s)
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1 At 100 muM, it activated 16% of the maximal current activated by nicotine. Nicotine latexin Homo sapiens
2 In contrast, NNN was a pure inhibitor of this nAChR subtype, with IC50 of approximately 1 nM in the presence of 10 muM nicotine. Nicotine latexin Homo sapiens