Title : Flavocoxid Protects Against Cadmium-Induced Disruption of the Blood–Testis Barrier and Improves Testicular Damage and Germ Cell Impairment in Mice [corrected].

Pub. Date : 2015 Nov

PMID : 26424772






2 Functional Relationships(s)
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1 Flavocoxid is a flavonoid that induces a balanced inhibition of cyclooxygenase (COX)-1 and COX-2 peroxidase moieties and of 5-lipoxygenase (LOX) and has efficacy in the male genitourinary system. flavocoxid cytochrome c oxidase II, mitochondrial Mus musculus
2 Flavocoxid administration reduced, in a time-dependent way, p-ERK 1/2, TNF-alpha, COX-2, 5-LOX, MDA, Bax, FSH, LH, TGF-beta3, augmented Bcl-2, testosterone, inhibin B, occludin, N-Cadherin, and improved the structural organization of the testis and the blood-testis barrier. flavocoxid cytochrome c oxidase II, mitochondrial Mus musculus