Title : NBCe1 expression is required for normal renal ammonia metabolism.

Pub. Date : 2015 Oct 1

PMID : 26224717






1 Functional Relationships(s)
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1 Examination of proteins involved in renal ammonia metabolism showed decreased expression of phosphate-dependent glutaminase and phosphoenolpyruvate carboxykinase, key enzymes in proximal tubule ammonia generation, and increased expression of glutamine synthetase, which recycles intrarenal ammonia and regenerates glutamine. Ammonia glutamate-ammonia ligase (glutamine synthetase) Mus musculus