Title : Apocynin attenuates cholesterol oxidation product-induced programmed cell death by suppressing NF-κB-mediated cell death process in differentiated PC12 cells.

Pub. Date : 2015 Oct

PMID : 26122972






1 Functional Relationships(s)
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1 7-Ketocholesterol and 25-hydroxycholesterol decreased the levels of Bid and Bcl-2, increased the levels of Bax and p53, and induced loss of the mitochondrial transmembrane potential, release of cytochrome c and activation of caspases (-8, -9 and -3). 25-hydroxycholesterol BCL2, apoptosis regulator Rattus norvegicus