Title : Overexpression of protein tyrosine phosphatase 1B impairs glucose-stimulated insulin secretion in INS-1 cells.

Pub. Date : 2016 Mar

PMID : 26099503






1 Functional Relationships(s)
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1 Compared with control cells, INS-1 cells overexpressing PTP1B showed decrease in insulin-stimulated tyrosine phosphorylation of the insulin receptor (IR) and insulin receptor substrate-1(IRS-1) by 56.4% and 53.1%, respectively. Tyrosine insulin receptor substrate 1 Rattus norvegicus