Title : Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTR up-regulation and astrocyte-mediated inflammation.

Pub. Date : 2015 Sep 1

PMID : 26063761






2 Functional Relationships(s)
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1 Fingolimod (FTY720), a modulator of sphingosine-1 phosphate (S1P) receptors, has been shown to increase BDNF levels and to reduce astrogliosis, proving its potential to regulate trophic support and inflammatory response. Fingolimod Hydrochloride brain derived neurotrophic factor Mus musculus
2 Fingolimod (FTY720), a modulator of sphingosine-1 phosphate (S1P) receptors, has been shown to increase BDNF levels and to reduce astrogliosis, proving its potential to regulate trophic support and inflammatory response. Fingolimod Hydrochloride brain derived neurotrophic factor Mus musculus