Title : Time-dependent changes in inhibitory action of lipopolysaccharide on intestinal motility in rat.

Pub. Date : 2015 Nov

PMID : 26051129






1 Functional Relationships(s)
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1 In conclusion, LPS induces COX-2 to produce PGE2, which initially activates EP2 and/or EP4 on smooth muscle cells to inhibit the contractility in early phase of LPS exposure. Dinoprostone prostaglandin-endoperoxide synthase 2 Rattus norvegicus