Title : Genetic Variation in Glutamate Carboxypeptidase II and Interaction with Dietary Natural Vitamin C May Predict Risk for Adenomatous Polyp Occurrence.

Pub. Date : 2015

PMID : 26028103






3 Functional Relationships(s)
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1 BACKGROUND: The C1561T variant of the glutamate carboxypeptidase II (GCPII) gene is critical for natural methylfolylpolyglutamte (methylfolate) absorption, and has been associated with perturbations in folate metabolism and disease susceptibility. Folic Acid folate hydrolase 1 Homo sapiens
2 BACKGROUND: The C1561T variant of the glutamate carboxypeptidase II (GCPII) gene is critical for natural methylfolylpolyglutamte (methylfolate) absorption, and has been associated with perturbations in folate metabolism and disease susceptibility. Folic Acid folate hydrolase 1 Homo sapiens
3 Therefore, this study examined whether C1561T-GCPII influences folate metabolism and adenomatous polyp occurrence. Folic Acid folate hydrolase 1 Homo sapiens