Title : A single nucleotide polymorphism in 3' untranslated region of epithelial growth factor receptor confers risk for pulmonary hypertension in chronic obstructive pulmonary disease.

Pub. Date : 2015

PMID : 25925667






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 METHODS AND RESULTS: In this study, we validated EGFR as a target of miR-214 in pulmonary artery smooth muscle cell (PASMC), which was further confirmed by the observation that exogenous overexpression of miR-214 significantly downregulated the expression of EGFR in the PASMCs genotyped as TT or TC, but not in CC group. Technetium microRNA 214 Homo sapiens
2 METHODS AND RESULTS: In this study, we validated EGFR as a target of miR-214 in pulmonary artery smooth muscle cell (PASMC), which was further confirmed by the observation that exogenous overexpression of miR-214 significantly downregulated the expression of EGFR in the PASMCs genotyped as TT or TC, but not in CC group. Technetium microRNA 214 Homo sapiens