Title : Potential role for snoRNAs in PKR activation during metabolic stress.

Pub. Date : 2015 Apr 21

PMID : 25848059






2 Functional Relationships(s)
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1 We also demonstrated that a subset of identified snoRNAs bind and activate PKR in vitro; the presence of a 5"-triphosphate enhanced PKR activity compared with the activity with a 5"-monophosphate, for some, but not all, snoRNAs. 5"-triphosphate eukaryotic translation initiation factor 2 alpha kinase 2 Homo sapiens
2 We also demonstrated that a subset of identified snoRNAs bind and activate PKR in vitro; the presence of a 5"-triphosphate enhanced PKR activity compared with the activity with a 5"-monophosphate, for some, but not all, snoRNAs. 5"-triphosphate eukaryotic translation initiation factor 2 alpha kinase 2 Homo sapiens