Title : Icariin intervenes in cardiac inflammaging through upregulation of SIRT6 enzyme activity and inhibition of the NF-kappa B pathway.

Pub. Date : 2015

PMID : 25688369






1 Functional Relationships(s)
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1 ICA upregulated the expression of SIRT6 and had an inhibitory effect on NF-kappaB inflammatory signaling pathways as shown by decreasing mRNA levels of the NF-kappaB downstream target genes TNF-alpha, ICAM-1, IL-2, and IL-6. icariin tumor necrosis factor Homo sapiens