Title : Glycated albumin triggers fibrosis and apoptosis via an NADPH oxidase/Nox4-MAPK pathway-dependent mechanism in renal proximal tubular cells.

Pub. Date : 2015 Apr 15

PMID : 25681565






1 Functional Relationships(s)
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1 GA-induced alpha-SMA, FN, TGF-beta and caspase 3 expressions were completely suppressed by the NADPH oxidase inhibitor apocynin (Apo), the reactive oxygen species (ROS) scavenger N-acetylcysteine (NAC) and the latent antioxidant Astragaloside IV (AS-IV). Acetylcysteine caspase 3 Homo sapiens