Title : VEGFR inhibitors upregulate CXCR4 in VEGF receptor-expressing glioblastoma in a TGFβR signaling-dependent manner.

Pub. Date : 2015 Apr 28

PMID : 25676691






1 Functional Relationships(s)
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1 VEGFR signaling inhibitors (Cediranib and Vandetanib) elevated the expression of CXCR4 in VEGFR-expressing GBM cell lines and tumors, and enhanced the in vitro migration of these lines toward CXCL12. vandetanib C-X-C motif chemokine ligand 12 Homo sapiens