Title : Combination effects of SMAC mimetic birinapant with TNFα, TRAIL, and docetaxel in preclinical models of HNSCC.

Pub. Date : 2015 Mar

PMID : 25431358






1 Functional Relationships(s)
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1 We investigated the effects of birinapant, a novel, second mitochondria-derived activator of caspases (SMAC)-mimetic that targets inhibitor of apoptosis proteins, alone and in combination with TNFalpha, TRAIL, or chemotherapy docetaxel. birinapant diablo, IAP-binding mitochondrial protein Mus musculus