Title : Combination therapy targeting ectopic ATP synthase and 26S proteasome induces ER stress in breast cancer cells.

Pub. Date : 2014 Nov 27

PMID : 25429617






1 Functional Relationships(s)
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1 We further showed that the combination of citreoviridin and the 26S proteasome inhibitor bortezomib could improve the anticancer activity by enhancing ER stress, by ameliorating citreoviridin-caused cyclin D3 compensation, and by contributing to CDK1 deactivation and PCNA downregulation. Bortezomib cyclin dependent kinase 1 Homo sapiens