Title : SH2 domain-containing protein tyrosine phosphatase 2 and focal adhesion kinase protein interactions regulate pulmonary endothelium barrier function.

Pub. Date : 2015 Jun

PMID : 25317600






1 Functional Relationships(s)
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1 Inhibition of the protein tyrosine phosphorylase SH2 domain-containing protein tyrosine phosphatase 2 (SHP2) increases tyrosine phosphorylation of vascular endothelial cadherin and beta-catenin, resulting in disruption of the endothelial monolayer and edema formation in the pulmonary endothelium. Tyrosine catenin beta 1 Homo sapiens