Title : Rad5 plays a major role in the cellular response to DNA damage during chromosome replication.

Pub. Date : 2014 Oct 23

PMID : 25310987






2 Functional Relationships(s)
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1 Here, we show that Rad5(HLTF/SHPRH), which mediates the error-free branch, has a major role in the response to DNA damage caused by methyl methanesulfonate (MMS) during chromosome replication, whereas translesion synthesis polymerases make only a minor contribution. Methyl Methanesulfonate SNF2 histone linker PHD RING helicase Homo sapiens
2 Here, we show that Rad5(HLTF/SHPRH), which mediates the error-free branch, has a major role in the response to DNA damage caused by methyl methanesulfonate (MMS) during chromosome replication, whereas translesion synthesis polymerases make only a minor contribution. Methyl Methanesulfonate SNF2 histone linker PHD RING helicase Homo sapiens