Title : Adrenergic signaling promotes angiogenesis through endothelial cell-tumor cell crosstalk.

Pub. Date : 2014 Oct

PMID : 25179535






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Inhibitors of beta2-adrenergic receptor (beta2-AR), protein kinase A (PKA), and mTOR could reverse norepinephrine-induced Jagged 1 upregulation, indicating that the beta2-AR-PKA-mTOR pathway participates in this process. Norepinephrine adrenoceptor beta 2 Homo sapiens
2 Inhibitors of beta2-adrenergic receptor (beta2-AR), protein kinase A (PKA), and mTOR could reverse norepinephrine-induced Jagged 1 upregulation, indicating that the beta2-AR-PKA-mTOR pathway participates in this process. Norepinephrine adrenoceptor beta 2 Homo sapiens
3 Inhibitors of beta2-adrenergic receptor (beta2-AR), protein kinase A (PKA), and mTOR could reverse norepinephrine-induced Jagged 1 upregulation, indicating that the beta2-AR-PKA-mTOR pathway participates in this process. Norepinephrine adrenoceptor beta 2 Homo sapiens
4 These data demonstrate that tumor angiogenesis mediated by the Jagged 1/Notch intercellular signaling is governed by the norepinephrine-activated beta2-AR-PKA-mTOR pathway. Norepinephrine adrenoceptor beta 2 Homo sapiens