Title : Primary sensory neurons regulate Toll-like receptor-4-dependent activity of glial cells in dorsal root ganglia.

Pub. Date : 2014 Oct 24

PMID : 25171787






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 LPS stimulated prostaglandin E2 (PGE2) production from DRG glial cells in a TLR4- and COX-2-dependent manner. Dinoprostone prostaglandin-endoperoxide synthase 2 Rattus norvegicus
2 LPS stimulated prostaglandin E2 (PGE2) production from DRG glial cells in a TLR4- and COX-2-dependent manner. Dinoprostone prostaglandin-endoperoxide synthase 2 Rattus norvegicus
3 In addition, exogenous PGE2 potentiated LPS-stimulated COX-2 mRNA while inhibiting TNFalpha mRNA expression by DRG cells, suggestive of a complex regulatory system to control inflammation within the DRG. Dinoprostone prostaglandin-endoperoxide synthase 2 Rattus norvegicus