Title : Inhibition of endothelial lipase activity by sphingomyelin in the lipoproteins.

Pub. Date : 2014 Oct

PMID : 25167836






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Using recombinant human EL, we showed that sphingomyelin inhibits the hydrolysis of PtdCho in the liposomes in a concentration-dependent manner. ptdcho lipase G, endothelial type Homo sapiens
2 Analysis of molecular species of PtdCho hydrolyzed by EL in the lipoproteins showed that the enzyme preferentially hydrolyzed PtdCho containing polyunsaturated fatty acids (PUFA) such as 22:6, 20:5, 20:4 at the sn-2 position, generating the corresponding PUFA-lyso PtdCho. ptdcho lipase G, endothelial type Homo sapiens