Title : Hsp27 regulates EGF/β-catenin mediated epithelial to mesenchymal transition in prostate cancer.

Pub. Date : 2015 Mar 15

PMID : 25130271






1 Functional Relationships(s)
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1 Moreover, silencing Hsp27 decreases EGF dependent phosphorylation of beta-catenin on tyrosine 142 and 654, enhances beta-catenin ubiquitination and degradation, prevents beta-catenin nuclear translocation and binding to the Slug promoter. Tyrosine epidermal growth factor Homo sapiens