Title : Glucose rapidly induces different forms of excitatory synaptic plasticity in hypothalamic POMC neurons.

Pub. Date : 2014

PMID : 25127258






4 Functional Relationships(s)
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1 Glucose rapidly induces different forms of excitatory synaptic plasticity in hypothalamic POMC neurons. Glucose proopiomelanocortin Homo sapiens
2 Brain glucose-sensing plays an essential role in the maintenance of normal body weight and metabolism; however, the effect of glucose on synaptic transmission in POMC neurons is largely unknown. Glucose proopiomelanocortin Homo sapiens
3 Here we identified three types of POMC neurons (EPSC(+), EPSC(-), and EPSC(+/-)) based on their glucose-regulated spontaneous excitatory postsynaptic currents (sEPSCs), using whole-cell patch-clamp recordings. Glucose proopiomelanocortin Homo sapiens
4 These data indicate that glucose induces distinct excitatory synaptic plasticity in different subpopulations of POMC neurons. Glucose proopiomelanocortin Homo sapiens