Pub. Date : 2014 Dec
PMID : 25034832
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oxymatrine lightened the inflammatory response of LPS-induced mastitis in mice through affecting NF-kappaB and MAPKs signaling pathways. | oxymatrine | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 2 | Oxymatrine inhibited the phosphorylation of NF-kappaB p65 and IkappaB in NF-kappaB signal pathway and reduced the phosphorylation of p38, ERK, and JNK in mitogen-activated protein kinase (MAPKs) signal pathway. | oxymatrine | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 3 | Oxymatrine inhibited the phosphorylation of NF-kappaB p65 and IkappaB in NF-kappaB signal pathway and reduced the phosphorylation of p38, ERK, and JNK in mitogen-activated protein kinase (MAPKs) signal pathway. | oxymatrine | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 4 | The results showed that oxymatrine had a protective effect on LPS-induced mastitis, and the anti-inflammatory mechanism of oxymatrine was related to the inhibition of NF-kappaB and MAPKs signal pathways. | oxymatrine | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |